Vacuolar biogenesis in yeast: Sorting out the sorting proteins
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Vacuolar biogenesis in yeast: Sorting out the sorting proteins
Roughly 10 years ago, a small number of yeast labs isolated a collection of mutants that missort the enzyme carboxypeptidase Y (CPY) in an attempt to unravel vacuolar protein sorting, a process that is closely related to lysosomal enzyme sorting in mammals. They came up with an overwhelming number of VfS genes-more than 50 so far-and the screen is not saturated (see Stack et al., 1995b). How ca...
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ژورنال
عنوان ژورنال: Cell
سال: 1995
ISSN: 0092-8674
DOI: 10.1016/0092-8674(95)90088-8